Based on the novel by Hubert Selby Jr., this gritty drama concerns four people trapped by their addictions. Harry (Jared Leto), and his best friend Tyrone (Marlon Wayans) are impoverished heroin addicts living in Coney Island, NY, while Harry's girlfriend Marion (Jennifer Connelly) is a fellow addict trying to distance herself from her wealthy father. Harry dreams of scoring a pound of smack, from which he could make enough money to open a clothing...

Season 1 of this intense HBO drama focuses on 17-year-old Rue Bennett (multimedia star Zendaya), a drug addict fresh from rehab who's struggling to stay clean. Ahead of the second season, the Emmy-winning series returns with two special episodes set over the Christmas holiday. Season 2 continues to follow Rue's dynamic group of friends as they enter a new year and question their choices.

After the tragic overdose of his estranged friend, Will, a recovering addict, returns home, where he is reunited with Claire, his friend's grieving mother, with whom he begins a secret but volatile affair.

In 1986, at the age of 56, Helen Travis became a Benedictine Sister after she lost her husband and both her sons to substance abuse. Two years later, in New York City, she opened a halfway house for recovering male addicts.

The up-and-down and then up-again story of musician Dewey Cox. Dewey's songs would change a nation. On his rock 'n roll spiral, Dewey sleeps with 411 women, marries three times, has 22 kids and 14 step-kids, stars in his own 70s TV show, collects friends ranging from Elvis to the Beatles to a chimp. He becomes addicted to and then kicks about every drug known to man. Despite it all, Cox grows into a national icon and eventually earns the love of a...

Haunted by his mother's ghost, a former drug addict returns to his hometown seeking redemption from his family. His return is not as he expected, as his true love has become his sister-in-law.

After blowing every chance at love and happiness- and burning every bridge in Hollywood- Hank Moody is finally ready to put the past to bed. But, as always, old indiscretions turn up to bit him squarely in the ass. Can Hank overcome his many vices and pull off a happy ending?

Christy is a single mom whose newly found sobriety has given her the ability to see her life clearly, and she does not like the view. Now she must untangle years of reckless decisions to make a better life for her and her kids. She has many challenges: stop drinking in wine country; a romance with her unavailable boss, raise her young son and troubled teenage daughter to make smart choices; and forgive her estranged mother, Bonnie, for her lack of...

Single mom Christy Plunkett is now sober and trying to get her life on track. However, she's tested daily by her newly sober mother, Bonnie, and by her relationships with her own kids. Christy tries to remain positive as she attempts to overcome her past and build a better future, but with her dysfunctional family and life's many setbacks, it's always an uphill battle.

Sophisticated and unique, this comedy centers on novelist Hank Moody (David Duchovny) who struggles to raise his 13-year-old daughter, while still carrying a torch for his ex-girlfriend. His obsession with truth-telling and self destructive behavior -- drinks drugs and relationships -- are both destroying and enriching to his career.