When his father brings home an ailing, newborn donkey, Louie names the animal Winslow and takes care of him, but everyone, including Louie's quirky friend Nora, thinks Winslow is not going to survive.

Follows the efforts of twelve-year-old Reena, who has recently moved to rural Maine, to adjust to a new environment while unexpectedly bonding with an ornery cow.

With the help of her wise old grandmother, twelve-year-old Rosie manages to work out some problems in her relationship with her best friend, Bailey, the boy next door.